EARLY INSIGHT

EARLY INSIGHT

A FLEXIBLE, MODULAR PLATFORM TO DISRUPT THE BLOCKBUSTER MANUFACTURING MODEL

Nick Rollings, Colin Barker and Richard Vellacott discuss the drug delivery scenario in the advanced therapy (AT) era, examining how the current slow-moving blockbuster treatment model is making way for a fast-moving, patient-focused era of personalised medicine

EARLY INSIGHT

SKIN-MOUNTABLE FLEXIBLE NEEDLE PATCH FOR MINIMALLY INVASIVE CONTROLLED DRUG DELIVERY

Chi Hwan Lee and Eun Kwang Lee introduce a skin-mountable flexible needle patch and discuss its applications in non-invasive drug delivery applications.

EARLY INSIGHT

Mark Stansfield

Otitopic

REDUCING VASCULAR MORTALITY IN PATIENTS WITH SUSPECTED ACUTE MI

Mark Stansfield and Kambiz Yadidi discuss initial results of their pilot Phase I clinical study of dry powder inhalation formulation of aspirin for the treatment of acute myocardial infarction.

EARLY INSIGHT

Sarah Trenfield

FabRx

PERSONALISING DRUG PRODUCTS USING 3D PRINTING

Sarah Trenfield and Abdul Basit look at the potential applications of 3D-printing technology to create personalised drug therapies in fields such as multiple drug therapy and paediatric/geriatric care and introduce FabRx’s 3D-printing system, which can produce formulations to suit a variety of situations.

EARLY INSIGHT

Frazer P Coutinho

BOTU

TARGETING DRUGS TO DISEASED OCULAR CELLS

Frazer Coutinho, Colin Green and Ilva Rupenthal discuss the targeted delivery of ocular therapeutics to diseased cells, using the cell-penetrating peptide, Xentry.

EARLY INSIGHT

Dr Andrew K Dickerson

Fluids and Structures (FaST) Laboratory

CITRUS FRUITS INSPIRE THE NEXT GENERATION OF AIRBORNE DRUG DELIVERY

Andrew Dickerson discusses recent research undertaken by his team into the mechanics of liquid microjets created naturally by citrus fruits, and how they could be the key to a new design of drug delivery device.

EARLY INSIGHT

Dr Blair Brettmann

Georgia Institute of Technology

ELECTROSPINNING: A PROMISING APPROACH TO CONTINUOUS MANUFACTURING FOR PHARMACEUTICALS

Blair Brettmann discusses the present advantages and challenges, as well as the future potential, of electrospinning as a continuous manufacturing technique for the pharmaceutical industry.

EARLY INSIGHT

Dr Kian Min Lim

PA Consulting

LISTEN TO YOUR INHALER, IT MIGHT BE TELLING YOU SOMETHING

Kian Min Lim and David Harris discuss how tailored algorithms can accurately detect inhalers’ acoustic signatures, effectively adding connectivity without having to add a chip to the inhaler.

EARLY INSIGHT

Dr Moe Wehbe

Microdermics

AN INTRADERMAL PLATFORM BUILT FOR INDUSTRY AND PATIENTS

Moe Wehbe, Iman Mansoor and Sahan Ranamukha discuss the potential of intradermal injection for modern medicines and its advantages over the subcutaneous route.

EARLY INSIGHT

Dr Mark Prausnitz

Micron Biomedical

SIMPLIFIED DRUG AND VACCINE DELIVERY USING MICRON’S MICRONEEDLE PATCH

Devin V McAllister, Sebastien Henry and Mark Prausnitz introduce the company’s dissolving microneedle patch technology, which has global potential, including in the developing world, across a range of vaccine and therapeutic applications.

OCULAR

Dr Robert Langer

Kala Pharmaceuticals

BREAKTHROUGH NANOTECHNOLOGY ENHANCES DELIVERY TO THE FRONT AND BACK OF THE EYE

Hongming Chen and Robert Langer discuss applications of the company’s Mucus Penetrating Particle nanotechnology in ophthalmic drug delivery.