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Gattefossé Pharma

SKIN

EXPERT VIEW
WEARABLE INJECTORS: CHOOSING & TESTING OPTIMAL ADHESIVES
Neal Carty and Deepak Prakash highlight the importance of choosing and testing adhesives for optimal wearable drug delivery device performance.
#100 Gattefosse featured
SKIN
SYNERGISING EXCIPIENTS TO BOOST SKIN DELIVERY
Cécile Morin and Delphine Marchaud discuss combining polar and apolar excipients in topical formulations in order produce synergies that maximise the performance of the drug.
AN INJECTION OF CONNECTED NEEDLE-FREE INNOVATION
CONNECTIVITY
Barbara Taylor
Portal Instruments
AN INJECTION OF CONNECTED NEEDLE-FREE INNOVATION
Barb Taylor discusses the next generation of needle-free injection devices, which incorporate connectivity.
SKIN-MOUNTABLE FLEXIBLE NEEDLE PATCH FOR MINIMALLY INVASIVE CONTROLLED DRUG DELIVERY
EARLY INSIGHT
Dr Chi Hwan Lee
Weldon School of Biomedical Engineering
SKIN-MOUNTABLE FLEXIBLE NEEDLE PATCH FOR MINIMALLY INVASIVE CONTROLLED DRUG DELIVERY
Chi Hwan Lee and Eun Kwang Lee introduce a skin-mountable flexible needle patch and discuss its applications in non-invasive drug delivery applications.
DISSOLVABLE MICRONEEDLES: APPLICATIONS AND OPPORTUNITIES
SKIN
Dr Jung Dong Kim
Raphas
DISSOLVABLE MICRONEEDLES: APPLICATIONS AND OPPORTUNITIES
Jung Dong Kim and Do Hyeon Jeong discuss dissolvable microneedle technology and its myriad uses.
SILICA NANO-SOLUTIONS FOR SKIN DELIVERY
SKIN
Dr Aparajita Khatri
Ceramisphere Health
SILICA NANO-SOLUTIONS FOR SKIN DELIVERY
Aparajita Khatri and Christophe A Barbé outline the growth of the dermal delivery market, as well as the challenges it faces. The authors go on to detail a nanocomposite lidocaine patch.
AN INTRADERMAL PLATFORM BUILT FOR INDUSTRY AND PATIENTS
EARLY INSIGHT
Dr Moe Wehbe
Microdermics
AN INTRADERMAL PLATFORM BUILT FOR INDUSTRY AND PATIENTS
Moe Wehbe, Iman Mansoor and Sahan Ranamukha discuss the potential of intradermal injection for modern medicines and its advantages over the subcutaneous route.
SIMPLIFIED DRUG AND VACCINE DELIVERY USING MICRON’S MICRONEEDLE PATCH
EARLY INSIGHT
Dr Mark Prausnitz
Micron Biomedical
SIMPLIFIED DRUG AND VACCINE DELIVERY USING MICRON’S MICRONEEDLE PATCH
Devin V McAllister, Sebastien Henry and Mark Prausnitz introduce the company’s dissolving microneedle patch technology, which has global potential, including in the developing world, across a range of vaccine and therapeutic applications.
COST-EFFECTIVE APPROACHES FOR SUCCESSFUL GENERIC DERMAL DRUG PRODUCT AUTHORISATIONS
SKIN
Prof Marc Brown
MedPharm
COST-EFFECTIVE APPROACHES FOR SUCCESSFUL GENERIC DERMAL DRUG PRODUCT AUTHORISATIONS
Marc Brown, Jon Lenn and Jeremy Dummond discuss various methods and advantages of in vitro bioequivalence studies for topical skin application, and how MedPharm’s unique technologies and experience can be invaluable in the effective development of generics in this field.
QUALITY BY DESIGN IN TDS DEVELOPMENT: BENEFIT OR BUREAUCRATIC BURDEN?
EXPERT VIEW
Petra Botzem
QUALITY BY DESIGN IN TDS DEVELOPMENT: BENEFIT OR BUREAUCRATIC BURDEN?
Petra Botzem and Thomas Hille discuss the Quality-by-Design approach to the development of transdermal drug delivery systems as laid out in ICH guideline Q8.
TERIPARATIDE MICRO-PATCH™: A SOLID MICRONEEDLE PRODUCT NEARING CLINICAL TRIALS
SKIN
Dr Faz Chowhury
Nemaura Pharma
TERIPARATIDE MICRO-PATCH™: A SOLID MICRONEEDLE PRODUCT NEARING CLINICAL TRIALS
Faz Chowdhury details a Micro-Patch™ solid formulation of the parathyroid hormone analogue, teriparatide, for the treatment of osteoporosis.
VACCINE DELIVERY USING THE NEMAURA SOLID DOSE INJECTOR
MICRONEEDLES
David Scott
Nemaura Pharma
VACCINE DELIVERY USING THE NEMAURA SOLID DOSE INJECTOR
Joanne Broadhead and Karmen Cheung report an investigation into the delivery of two vaccines using Nemaura Pharma’s solid-dose injection technology.
THE RAPID EVOLUTION OF THE TRANSDERMAL DRUG DELIVERY INDUSTRY SPAWNS INNOVATION
MICRONEEDLES
Luis Tissone
Trelleborg Sealing Solutions
THE RAPID EVOLUTION OF THE TRANSDERMAL DRUG DELIVERY INDUSTRY SPAWNS INNOVATION
Luis Tissone outlines technological developments behind microneedle design including the use of advanced liquid silicone rubber (LSR) and two-component injection technology, and explores the advantages this route offers over traditional intramuscular routes.
THE CRITICALITY OF ADHESIVE SELECTION FOR OPTIMAL TRANSDERMAL DRUG DELIVERY SYSTEMS
TRANSDERMAL
Megan Greth
ARx
THE CRITICALITY OF ADHESIVE SELECTION FOR OPTIMAL TRANSDERMAL DRUG DELIVERY SYSTEMS
Megan Greth and Gozde Karabiyik discuss why selecting the right adhesive for body-worn drug delivery systems – be they transdermal patches or wearable injection devices or pumps – is critical for a successful outcome.
OPTIMISING <i>IN VITRO</i> TESTING FOR TRANSDERMAL AND TOPICAL DRUG PRODUCTS
TRANSDERMAL
Tony Copley
Copley Scientific
OPTIMISING IN VITRO TESTING FOR TRANSDERMAL AND TOPICAL DRUG PRODUCTS
Tony Copley examines the regulatory framework for transdermal and topical products and popular, effective and cost-efficient in vitro testing techniques for quantifying their release characteristics.
NEW RESEARCH TOOLS FOR TOPICAL & TRANSDERMAL DEVELOPMENT
TRANSDERMAL
Prof Marc Brown
MedPharm
NEW RESEARCH TOOLS FOR TOPICAL & TRANSDERMAL DEVELOPMENT
Marc Brown, Rob Turner and James Gibbons provide a view on the current topical and transdermal market, elaborate on some of the common approaches to product development in this area, and reveal the company’s newest model, the MedFlux-HT™ system.
MICROBRISTLE APPLICATOR (MBA™) SYSTEMS FOR TOPICAL AND TRANSDERMAL DRUG APPLICATION
TRANSDERMAL
Pierre Michelet
GEKA Healthcare
MICROBRISTLE APPLICATOR (MBA™) SYSTEMS FOR TOPICAL AND TRANSDERMAL DRUG APPLICATION
Pierre Michelet, Karl Hartstock-Martin, and Moritz Beyhl present the innovative technology of microbristle applicators (MBA™) for a more precise and hygienic application within topical and transdermal treatment. MBA™ comprises a platform of moulded, pure plastic applicators with very fine bristles to apply liquid and semi-liquid formulations.
MEETING EVOLVING BIOLOGICS & SMALL MOLECULES NEEDS
MICRONEEDLES
Dr Lisa A Dick
3M Drug Delivery Systems
MEETING EVOLVING BIOLOGICS & SMALL MOLECULES NEEDS
Lisa A Dick provides a run-down of the concept, design and development of the company’s microneedle drug delivery platform, both hollow and solid needle arrays, including recent clinical trials of the hollow-needle device.
AQUARMED™: TRANSDERMAL DELIVERY USING NOVEL COMPONENTS
TRANSDERMAL
Prof Marc Brown
MedPharm
AQUARMED™: TRANSDERMAL DELIVERY USING NOVEL COMPONENTS
Marc Brown, Adrian Williams and James Gibbons explain how the company has developed AquaRMed and describe the potential benefits it could offer patients and companies alike.
Q&A: SUCCESSFUL MASS PRODUCTION OF AN INNOVATIVE DRUG DELIVERY TECHNOLOGY
MICRONEEDLES
Dr Jung Dong Kim
Raphas
Q&A: SUCCESSFUL MASS PRODUCTION OF AN INNOVATIVE DRUG DELIVERY TECHNOLOGY
Jung Dong Kim answers questions about the company, its capabilities, and the mass production of an innovative dissolving microstructure drug delivery technology.
HIGHLY CUSTOMISABLE HOLLOW POLYMER MICRONEEDLE SOLUTIONS
MICRONEEDLES
Dr Marion Sausse Lhernould
Novinject
HIGHLY CUSTOMISABLE HOLLOW POLYMER MICRONEEDLE SOLUTIONS
Marion Sausse Lhernould, Serge Tailler, Michel Deleers and Alain Delchambre present a hollow microneedle delivery device manufactured using a novel proprietary process.
DERMAL DELIVERY OF BIOLOGICS
MICRONEEDLES
Dr Richard Toon
Nemaura Pharma
DERMAL DELIVERY OF BIOLOGICS
Faz Chowdhury and Richard Toon describe one of the company’s key technologies for the delivery of biologics, the Micropatch™.
PATRICK ALEXANDRE, CROSSJECT
INTERVIEW
Patrick Alexandre
Crossject
PATRICK ALEXANDRE, CROSSJECT
Shortly after Crossject’s successful IPO on the French NYSE Euronext Paris Exchange (Paris Bourse), Patrick Alexandre spoke about Crossject, its technology and strategy for the future as a publically traded company.
NOVEL TRANSDERMAL DELIVERY SYSTEMS FOR TREATMENT OF DIABETES
TRANSDERMAL
Dr Alan Smith
4P Therapeutics
NOVEL TRANSDERMAL DELIVERY SYSTEMS FOR TREATMENT OF DIABETES
Alan Smith outlines the stages of Type 2 diabetes treatment, progressing to extenatide and insulin injections, and makes the case, using clinical data, for the transdermal route as a viable alternative to injections.
TRANSDERMAL DELIVERY DEVICE DESIGN
EXPERT VIEW
Bruce K Redding
TRANSDERMAL DELIVERY DEVICE DESIGN
Bruce K Redding Jnr gives an overview of the different types of transdermal patch design, as well as the various methods of getting through the skin.
TRANSDERMAL DELIVERY AS A NEW SOURCE FOR BIOPHARMA INNOVATION
EXPERT VIEW
Dr Kevin Pang
TRANSDERMAL DELIVERY AS A NEW SOURCE FOR BIOPHARMA INNOVATION
Kevin Pang discusses the potential of transdermal delivery, how it has thus far failed to live up to it and how a combination of formulation and electronic advancements mean it could soon be realised.
DESIGNING AN ULTRASOUNDENABLED PATCH FOR INSULIN
TRANSDERMAL
Bruce K Redding
DESIGNING AN ULTRASOUNDENABLED PATCH FOR INSULIN
Bruce K Redding Jr tells the story of the design and development of the U-Strip™ Insulin Transdermal Delivery System.
YOUR SOLUTION FOR SUCCESSFUL INTRADERMAL DELIVERY
MICRONEEDLES
Dr Paul Vescovo
Debiotech
YOUR SOLUTION FOR SUCCESSFUL INTRADERMAL DELIVERY
Paul Vescovo and Laurent-Dominique Piveteau discuss the design of the Debioject™ microneedle device and inserter, and its applications, particularly in intradermal delivery of vaccines.
TECHNOLOGY SHOWCASE: CROSSJECT’S ZENEO<sup>®</sup>
SKIN
Dr Tim Muller
Crossject
TECHNOLOGY SHOWCASE: CROSSJECT’S ZENEO®
ZENEO® is a unique, automatic needle-free jet injector for SC, IM and ID routes, developed by Crossject. With ZENEO®, injection is fast, easy and secured.
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