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INJECTION

UNLOCKING THE POTENTIAL OF CONNECTED DRUG DELIVERY DEVICES FOR DIABETES
EXPERT VIEW
Paul Draper
UNLOCKING THE POTENTIAL OF CONNECTED DRUG DELIVERY DEVICES FOR DIABETES
Paul Draper discusses the current state of connected injection pens and devices in the diabetes space, exploring the benefits that connectivity can bring to drug delivery devices and considering how to exemplify good design in a connected injection device for diabetes drug therapies.
HOW TO NAVIGATE A COMPLEX CONNECTIVITY ENVIRONMENT
CONNECTIVITY
Pascal Dugand
Nemera
HOW TO NAVIGATE A COMPLEX CONNECTIVITY ENVIRONMENT
Pascal Dugand, Cécile Gross and Mark Tunkel consider the complexity of the landscape for connected devices and demonstrate how a balance can be achieved between patient needs, technology and the cost of integrating this technology into a device.
TIPS AND TRICKS FOR IMPLEMENTING SUSTAINABILITY INITIATIVES
SUSTAINABILITY
Henryk Badack
Vetter Pharma
TIPS AND TRICKS FOR IMPLEMENTING SUSTAINABILITY INITIATIVES
Henryk Badack outlines Vetter's efforts to establish sustainable business practices.
THE EVOLUTION OF THE PHARMA ECOSYSTEM: PRODUCT PERFORMANCE NOW MEETS SUSTAINABILITY
SUSTAINABILITY
Dr Bettine Boltres
West Pharmaceutical Services
THE EVOLUTION OF THE PHARMA ECOSYSTEM: PRODUCT PERFORMANCE NOW MEETS SUSTAINABILITY
Bettine Boltres and Shivani Polasani discuss how pharma can progress towards a more sustainable future, and consider the role that the collaboration between Corning and West Pharmaceutical Services can play in supporting pharma’s sustainability goals.
HOW LIFECYCLE ASSESSMENT SUPPORTS INSIGHT-DRIVEN SUSTAINABLE DESIGN
EXPERT VIEW
Paramesh Natarajan
HOW LIFECYCLE ASSESSMENT SUPPORTS INSIGHT-DRIVEN SUSTAINABLE DESIGN
Paramesh Natarajan, Shadi Bavar and Charlie Dean present the case for using screening lifecycle assessments to lead into more detailed targeted and comprehensive lifecycle assessments focused on the areas of greatest environmental impact, using a screening lifecycle assessment of a hypothetical body-worn injector as an example.
AN AUTOINJECTOR REVOLUTION: ADVANCED SIMULATION TECHNOLOGIES ENHANCING GLOBAL MANUFACTURING NETWORKS
INDUSTRIALISATION
Edwin Hendrawan
SHL Medical
AN AUTOINJECTOR REVOLUTION: ADVANCED SIMULATION TECHNOLOGIES ENHANCING GLOBAL MANUFACTURING NETWORKS
Edwin Hendrawan, Yi-Chi Lu and Christian Walter set out how SHL is building simulation capabilities, and describe how simulation will propel the business forward on every level, from individual shop floors to overall global expansion planning, in order to be able to meet the growing and increasingly complex demands from both pharma customers and patients.
INTERVIEW with Jeff Henderson
INTERVIEW
Jeff Henderson
Vetter Pharma
INTERVIEW with Jeff Henderson
Jeff Henderson discusses the practice of outsourcing within the pharmaceutical industry. He considers factors that pharma and biopharma companies should consider when determining whether or not to outsource to a CDMO and many of the advantages that outsourcing can offer, especially to small- and medium-sized companies.
AUTOINJECTORS FOR LARGE-VOLUME SUBCUTANEOUS DRUG DELIVERY
INJECTION
Ian Thompson
Ypsomed
AUTOINJECTORS FOR LARGE-VOLUME SUBCUTANEOUS DRUG DELIVERY
Ian Thompson provides a summary of a recent literature review on subcutaneous administration with dose volumes greater than 1.0 mL, which examines how previous studies have addressed the limitations and considerations for designing and developing large-volume autoinjectors.
Interview with Claire Raynal-Olive & Pierre-Yves Favennec
INTERVIEW
Claire Raynal-Olive
Aptar Pharma
Interview with Claire Raynal-Olive & Pierre-Yves Favennec
Claire Raynal-Olive and Pierre-Yves Favennec discuss the strategy and objectives of Aptar Pharma’s expansion programme of its global rubber component manufacturing, implementing advanced technology, increased capacity and local-for-local manufacturing capability.
AUTOMATING ASSEMBLY TO EXPEDITE TIME-TO-MARKET
INDUSTRIALISATION
Dr Dave Seaward
3P Innovation
AUTOMATING ASSEMBLY TO EXPEDITE TIME-TO-MARKET
Dave Seaward discusses how 3P innovation takes a holistic approach to solving the technical challenges encountered by its clients and looks for opportunities to enhance the final product, enable efficient processing and support commercially viable manufacturing.
TERUMO GLOBAL PARENTERAL CDMO – INTEGRATED INNOVATION
INDUSTRIALISATION
Michele Guasti
Terumo Medical Care Solutions
TERUMO GLOBAL PARENTERAL CDMO – INTEGRATED INNOVATION
Michele Guasti discusses the advantages that Terumo’s parenteral CDMO brings to customers due to its position as a single service provider from formulation to final product and its intimate understanding of Terumo’s range of prefillable polymer syringes.
COMPANY SHOWCASE: PCI PHARMA SERVICES
INDUSTRIALISATION
PCI Pharma Services
COMPANY SHOWCASE: PCI PHARMA SERVICES
PCI Pharma Services showcases its portfolio of drug delivery-relevant solutions, including: sterile fill-finish and lyophilisation; drug-device combination product design and development; packaging for injectables; and Speedsolutions™ supply chain simplification, and highlights plans for expansion.
INTERVIEW: DOUG BRYANS, BRYLLAN & JOHN MERHIGE, CREDENCE
INTERVIEW
Dr Doug Bryans
Bryllan
INTERVIEW: DOUG BRYANS, BRYLLAN & JOHN MERHIGE, CREDENCE
Douglas Bryans and John Merhige discuss the changing needs of drug developers around novel dual-chamber and ready-to-use drug delivery devices, capacity and the delivery of complete solutions from CDMOs and device developers, anchored around the recently announced partnership between Credence MedSystems and Bryllan to provide these critical services.
NEW EXTRACTABLES DATA FOR OXYCAPT™ MULTILAYER PLASTIC VIAL FOR BIOLOGICS & GENE/CELL THERAPY
PREFILLED SYRINGES
Hiroki Hasegawa
Mitsubishi Gas Chemical
NEW EXTRACTABLES DATA FOR OXYCAPT™ MULTILAYER PLASTIC VIAL FOR BIOLOGICS & GENE/CELL THERAPY
Hiroki Hasegawa and Tomohiro Suzuki review the properties of OXYCAPT™, Mitsubishi Gas Chemical’s multilayer material for primary biologic packaging, and share the data from the latest study on OXYCAPT’s extractables profile.
PRIMARY PACKAGING CONSIDERATIONS FOR SUPPORTING COMPLIANCE TO ANNEX 1 REVISION
PREFILLED SYRINGES
Edouard Pagnoud
Aptar Pharma
PRIMARY PACKAGING CONSIDERATIONS FOR SUPPORTING COMPLIANCE TO ANNEX 1 REVISION
Edouard Pagnoud, Estelle Verger and Benjamin Brocco look at the new requirements associated with EMA GMP Annex 1 revision regarding injectable primary packaging for ensuring sterility and safety, and consider how Aptar's PremiumFill® can reduce the risk of contamination and defects.
RISING TO THE REGULATORY EVIDENCE CHALLENGE FOR HIGH-QUALITY COMBINATION PRODUCTS
PREFILLED SYRINGES
Victoria Morgan
West Pharmaceutical Services
RISING TO THE REGULATORY EVIDENCE CHALLENGE FOR HIGH-QUALITY COMBINATION PRODUCTS
Victoria Morgan and Stacy Gates-Rector explore how West is supporting pharma companies with packaging challenges through the supply of high-quality prefillable syringe plungers and provision of a highly co-ordinated technical documentation package.
BIOLOGIC INTEGRITY: MEASURING AND MANAGING THE HIDDEN LEACHABLES RISK FROM PFS ADHESIVE
INDUSTRIALISATION
Enrico Barichello
Stevanato Group
BIOLOGIC INTEGRITY: MEASURING AND MANAGING THE HIDDEN LEACHABLES RISK FROM PFS ADHESIVE
Enrico Barichello considers the often-overlooked influence of adhesive in the assembly of prefilled syringes and how the hidden risks can be managed and overcome.
COMBINING PLASTIC BAG FLEXIBILITY WITH GLASS STORAGE STABILITY – NEXT-GENERATION PACKAGING FOR SENSITIVE PREMIXED DRUGS
INJECTION
Pauline Koyanagi
ZACROS
COMBINING PLASTIC BAG FLEXIBILITY WITH GLASS STORAGE STABILITY – NEXT-GENERATION PACKAGING FOR SENSITIVE PREMIXED DRUGS
Pauline Koyanagi and Atsushi Mio look at the benefits of flexible drug packaging and discuss ZACROS’s MediTect™ packaging for sensitive liquid parenteral formulations.
“A CHILD IS NOT A SMALL ADULT”: CHALLENGES AND SOLUTIONS IN DEVELOPING DRUG DELIVERY DEVICES FOR CHILDREN
EXPERT VIEW
Tom Oakley
“A CHILD IS NOT A SMALL ADULT”: CHALLENGES AND SOLUTIONS IN DEVELOPING DRUG DELIVERY DEVICES FOR CHILDREN
Tom Oakley and Heather Jameson consider the main differences in developing therapies and drug delivery devices for children and babies when compared with adults.
Product Showcase: CCBio’s Omega & Salus Pen Injectors
INJECTION
Jimmy Fan
CC Bio
Product Showcase: CCBio’s Omega & Salus Pen Injectors
CCBio showcases two multidose injection devices with non-replaceable containers – the multi-dose pen, Omega, and the single-dose autoinjector, Salus.
ACQUIRING A LIQUID BIOPSY INCIDENTAL TO INTRAVITREAL INJECTION
EARLY INSIGHT
Dr Alex Tumlinson
ACQUIRING A LIQUID BIOPSY INCIDENTAL TO INTRAVITREAL INJECTION
Alexandre Tumlinson introduces Twenty/Twenty Therapeutics' VitreoDx injection system to address emerging trends in intravitreal therapeutics.
NEEDLESTICK INJURY RISKS: SAFEGUARDING HEALTHCARE WORKERS AND PATIENTS
INJECTION
Dr Fred Metzmann
Roncadelle
NEEDLESTICK INJURY RISKS: SAFEGUARDING HEALTHCARE WORKERS AND PATIENTS
Fred Metzmann discusses how using safety syringes can be a cost-effective measure to reduce the risk of injury to healthcare personnel and patients, and introduces the company’s devices designed for safer drug administration.
IN THE THICK OF IT: ACCELERATING THE MIXING AND DELIVERY OF HIGH-VISCOSITY INJECTABLES
DUAL CHAMBER
Dr Brent Buchine
Windgap Medical
IN THE THICK OF IT: ACCELERATING THE MIXING AND DELIVERY OF HIGH-VISCOSITY INJECTABLES
Brent Buchine, Miriam Silton, Jameson Woods and Andrew Ryan explore how the combination of gas power and a side-by-side cartridge configuration increases the working viscosity range for the mixing and delivery of complex injectable formulations.
TECHNOLOGICAL ADVANCEMENTS TO OVERCOME VISCOSITY CHALLENGES FOR INJECTABLE DEVICES
INJECTION
Joe Neale
Recipharm
TECHNOLOGICAL ADVANCEMENTS TO OVERCOME VISCOSITY CHALLENGES FOR INJECTABLE DEVICES
Joe Neale explores injectable drug development, delving into the intricacies of how technology is advancing to meet the challenges of administering complex formulations, enabling a more positive patient experience, promoting dosing compliance and maximising the benefits of these essential medicines.
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