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INJECTION
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CGT
INJECTION
DUAL CHAMBER
FORMULATION
PFS
WEARABLES
ALL INJECTION
OCULAR
ORAL
RESPIRATORY
PULMONARY
NASAL
ALL RESPIRATORY
SUSTAINABILITY
MORE
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PREFILLED SYRINGES
INJECTION
Jimmy Fan
Technology Showcase: I-Platform from CCBio – How to Upgrade a Device in One Platform
CCBio showcases its I-Platform injectable drug delivery solution comprising: delivery units, including the electronic, connected Tesla device; containers and adapters; and safety needles.
INDUSTRIALISATION
Drew Jelgerhuis
FROM SIMULATION TO SPRING SATISFACTION
Drew Jelgerhuis discusses the power of simulation to enhance a drug delivery device design project, including faster development times and reduced costs.
INDUSTRIALISATION
Thomas Rudolph
INDUSTRIALISATION OF PHARMACEUTICAL AND MEDICAL DEVICES IN THE SCIENTIFIC MOULDING APPROACH
Thomas Rudolph, Markus Reil, Stefan Schumann and Tobias Weigert discuss Gerresheimer’s strategy for managing potential risks across the entire product lifecycle.
INDUSTRIALISATION
Barry McDermott
INDUSTRIALISATION AND SCALE-UP OF DRUG DELIVERY DEVICES
Barry McDermott and Shari Krusniak look at the manufacturing processes involved in bringing a new drug delivery system and formulation to market.
INDUSTRIALISATION
Otto Abildgaard
EMBRACING OPPORTUNITIES PRESENTED BY DIGITALISATION: USING DATA TO DRIVE PERFORMANCE
Otto Abildgaard and Sebastian Berninger-Lund review the four-stage process Stevanato has developed to bring improvements in time to market through optimised manufacturing.
INDUSTRIALISATION
Tracy Pedreso
CONTINUOUS IMPROVEMENT: FROM ABSTRACTION TO REALITY
Tracy Pedreso discusses SHL Medical’s strategy for making continuous improvement a reality.
INDUSTRIALISATION
Mark Tunkel
HOLISTIC DEVELOPMENT & INDUSTRIALISATION OF DRUG DELIVERY DEVICES & COMBINATION PRODUCTS
Mark Tunkel and Niyati Sapatnekar discuss Nemera’s holistic approach to development and industrialisation.
INTERVIEW
Piyush Agarwal
INTERVIEW: Piyush Agarwal, Tjoapack
Piyush Agarwal talks with ONdrugDelivery about the current state of the injectable pharmaceuticals market and how working with a specialist contract packaging organisation can help pharma companies navigate their product through this rapidly evolving sector and deliver their product to market on time.
CONNECTIVITY
Aurelie Pager
A PATIENT-CENTRIC, CONNECTED INJECTION DEVICE FOR DECENTRALISED CLINICAL TRIALS – THE HUMAN FACTORS RESULTS ARE IN!
Aurélie Pager and Mircea Despa follow up on an article published in the December 2021 issue of ONdrugDelivery. BD has now completed a human factors study assessing the usability, acceptance and ease of use of its connected injection prototype for clinical trials.
INJECTION
Jonathan Kearns
PUTTING PROCESS ENGINEERING INTO ACTION
Jonathan Kearns and Kevin Huang consider how engineering competencies are being driven to the next level by leveraging process engineering and how this can transform drug-device projects.
PREFILLED SYRINGES
Sebastien Cordier
PREMIUMCOAT
®
SOLUTIONS: HELPING CONTROL THE LEVEL OF SILICONE TO PROTECT SENSITIVE THERAPEUTICS
Sébastien Cordier, Vincent Holterboch and Estelle Verger discuss how coated elastomer components, such as Aptar Pharma’s PremiumCoat
®
, can help drug developers optimise the balance between component processability and minimising silicone migration into a drug product.
INJECTION
Fred Metzmann
EXCELLENCE THROUGH SIMPLICITY: PICCOJECT™ AUTOINJECTOR PLATFORM
Fred Metzmann and Chris Muenzer discuss the simplicity of the PiccoJect™ autoinjector platform and the company's commitment to sustainability.
PREFILLED SYRINGES
Hiroki Hasegawa
OXYCAPT™: A SUPERIOR PRIMARY CONTAINER MATERIAL FOR BIOLOGICS AND GENE AND CELL THERAPIES
Hiroki Hasegawa and Tomohiro Suzuki provide an overview of the OXYCAPT multilayer vial and syringe, along with a discussion of how OXYCAPT fares at low and very low temperatures.
EXPERT VIEW
Martin Gonzalez
RECENT TRENDS & DEVELOPMENTS IN INJECTABLE FORMULATION & DELIVERY
Martin Gonzalez details current trends in sterile injectable formulations and their delivery devices, and the challenges pharma and its contract development and manufacturing company partners face in bringing emerging breakthroughs to market.
INTERVIEW
Steven Kaufman
INTERVIEW: STEVEN KAUFMAN, STEVANATO GROUP, & MICHAEL EARL, OWEN MUMFORD
In this exclusive interview, Steven Kaufman of Stevanato Group, and Michael Earl of Owen Mumford, talked with us about their companies' recent major agreement for the manufacturing and provision of prefillable syringes for the advanced two-step, single-use autoinjector, Aidaptus
®
.
SUSTAINABILITY
Fran Pencliffe
SUSTAINABILITY: WHAT CAN THE HEALTHCARE SECTOR LEARN FROM CONSUMER DESIGN?
Fran Penrose considers the lessons the healthcare sector can draw from the fast-moving consumer sector when designing for sustainability and asks, “Can we go even further?”
SUSTAINABILITY
Rob Doorakkers
SMART SOLUTIONS TO REDUCE CARBON FOOTPRINT
Rob Doorakkers and Geert van Amstel discuss why the company decided to become carbon neutral, how it is working to make injection moulding more sustainable and how the organisation is minimising its impact on the environment.
SUSTAINABILITY
Pierre Moulinie
DESIGNING DRUG DELIVERY DEVICES TO MEET EMERGING NEEDS AND SUSTAINABILITY GOALS
Pierre Moulinié, Isaac Platte and Lauren Zetts discuss how polycarbonate-based materials deliver value to emerging drug delivery devices.
SUSTAINABILITY
Emil Fraenkel
SUSTAINABILITY WITH THE ARIA AUTOINJECTOR: THE ROUTE TO FURTHER IMPROVEMENTS
Emil Fraenkel and Bjarne Sørensen investigate the route to further sustainability improvements for the Aria autoinjector. This article is a sequel to a benchmark study on the environmental impact of Aria presented by Phillips-Medisize in ONdrugDelivery Issue 126 (Oct/Nov 2021).
OCULAR
Andrea Allmendinger
HOW TEN23 HEALTH IS MEETING DEVELOPMENTAL CHALLENGES FOR INTRAVITREAL PRODUCTS
Andrea Allmendinger and Hanns-Christian Mahler highlight new regulatory and quality requirements for intravitreal applications and discuss technical challenges during drug product technical development and manufacturing.
OCULAR
Gautam Shetty
OPHTHALMIC INJECTION OF VISCOUS FORMULATIONS – WHY UNIQUE NEEDS REQUIRE A NOVEL DELIVERY APPROACH
Guatam Shetty and Richard Whelton outline the key considerations related to ophthalmic injection of viscous formulations and propose an innovative, user-validated and fully mechanical device-based solution.
EXPERT VIEW
Michael Neely
A VIEW ON THE USE OF APROTIC SOLVENTS IN PARENTERAL DRUG FORMULATIONS
Michael Neely presents a review and discussion of the status of aprotic solvents as a solubilising vehicle for parenteral drug formulations in the context of the industry’s increasing interest in biologic drugs.
INDUSTRIALISATION
Rob Doorakkers
HOW MODEL BASED DEFINITION REVOLUTIONISES THE PRODUCTION OF MEDICAL DEVICES
Rob Doorakkers looks at the advantages of the IGS GeboJagema’s Model Based Definition process and its ability to improve the quality of medical device production.
INJECTION
Asmita Khanolkar
COMPUTATIONAL MODELLING OF INJECTION-RELATED TISSUE RESPONSES IN DRUG DELIVERY
Olivia Jefferies, Elizabeth Margerison and Asmita Khanolkar introduce Oval’s work on using ultrasound scanning and finite element analysis to construct a model of how tissue compresses under use of an autoinjector across patient demographics, and how this may provide insights into improved autoinjector design for more accurate injection depths, improving patient outcomes.
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